*A study published in GeroScience has identified common biomarkers, such as cholesterol and glucose levels, in individuals who live past 90, commonly known as Centenarians.
Using data from 44,000 Swedish participants aged 64-99, researchers analyzed blood biomarkers linked to inflammation, metabolism, liver and kidney function, and other health factors to determine their relationship with longevity, Science Alert reports. Over 35 years, 1,224 participants (2.7%) reached 100 years, with most being female.
The study found that centenarians generally had lower levels of glucose, creatinine, and uric acid from their sixties onward. While median biomarker values didn’t show significant differences, centenarians rarely exhibited extreme values, such as glucose levels above 6.5 or creatinine levels above 125. This large-scale research provides new insights into factors associated with exceptional longevity.
The researchers wrote: “When exploring which biomarkers were linked to the likelihood of reaching 100, we found that all but two (alat and albumin) of the 12 biomarkers showed a connection to the likelihood of turning 100. This was even after accounting for age, sex and disease burden.” They added, “The people in the lowest out of five groups for levels of total cholesterol and iron had a lower chance of reaching 100 years as compared to those with higher levels. Meanwhile, people with higher levels of glucose, creatinine, uric acid and markers for liver function also decreased the chance of becoming a centenarian.”
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