
Deion Sanders Reveals New Health Concerns After TCU Game
*Colorado head coach Deion Sanders admitted after Saturday’s loss to TCU that he is battling significant pain. The Buffaloes are now 2-4 overall and 0-3 in the Big 12, and Sanders is dealing with renewed health struggles.
During his postgame press conference in Fort Worth, Sanders said, “I think I’ve got more blood clots. It don’t make sense. I’m hurting like crazy.” He explained that he isn’t getting enough blood flow to his leg and has a doctor’s appointment to assess the situation.
Despite his pain, Sanders tried to keep the focus on his team, saying, “I’m sorry to get that out, but thank you for noticing.”
Coach Prime says he thinks he has more blood clots and is seeing a doctor on Monday pic.twitter.com/nWXv1JrIuy
— DNVR Buffs (@DNVR_Buffs) October 5, 2025
Visible Pain on the Sideline Raises Questions
Throughout the second half against TCU, Sanders was visibly hurting and removed his left shoe on the sideline. He sat for parts of the game, prompting concern from fans and reporters, NBC Sports is reporting.
Sanders has previously undergone multiple procedures for blood clots in his left leg, including the amputation of two toes in 2021. The pain and swelling following Saturday’s game sparked fears of a possible recurrence.
As of this posting (10-06-25), no public updates have been shared about the doctor’s visit. However, if new clots are confirmed, it could mean more surgery and time away from the team.
Long History of Blood Clot Issues and Surgeries
Sanders has faced serious health issues since 2021 when blood clots in his left leg led to multiple surgeries and a lengthy hospital stay. In 2023, he battled more clots in his thighs and missed Pac-12 media day while recovering.
Earlier this year, Sanders also underwent surgery to treat bladder cancer, a condition he has since declared cured. Despite these setbacks, he returned to lead Colorado for the current season.
Doctors attribute Sanders’ recurring issues to peripheral artery disease, which blocks blood flow to tissues and can cause severe pain and tissue damage. Sanders has noted that even his elite athletic background doesn’t protect him from such health risks.

Team Struggles Compound the Pressure on Sanders
With a 2-4 overall record and three straight conference losses, Colorado’s season has been challenging. Sanders’ health issues add another layer of adversity for a team already facing high expectations.
Fans and players alike are expressing concern for Sanders, who continues to coach through pain while trying to stabilize the Buffaloes’ season. His resilience remains a key point of inspiration for the program.
Why Deion Sanders’ Health Journey Matters Beyond Football
Deion Sanders’ health struggles have resonated far beyond the football field. As a high-profile coach and former NFL star, his openness about blood clots, cancer, and chronic pain has helped raise awareness of serious health conditions that often go unnoticed in public figures.
Many fans see Sanders as a symbol of strength, but his transparency shows that even elite athletes face life-threatening medical challenges. His story encourages early detection, regular checkups, and listening to warning signs like leg pain or fatigue.
Sanders has used his platform to emphasize that health comes first, even in the competitive world of college football. His willingness to coach through pain while raising awareness makes his journey all the more impactful for fans, players, and the wider community.

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